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Perzebertinib

CAT: 0804-HY-163428-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-163428-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ZN-A-1041 inhibits HER2 in BT474 cell and wt-EGFR in H838 cells, with IC50s of 9.5 nM and 12 μM respectively. ZN-A-1041 can be used for research of cancer and inflammation[1].
CAS Number
2414056-31-6
Product Name Alternative
ZN-A-1041
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/zn-a-1041.html
Solubility
10 mM in DMSO
Smiles
COC1=C(C2=C(N=CN=C2NC3=CC(C)=C(C=C3)OC4=CC5=NC=NN5C=N4)C=C1)O[C@@H]6CCN(CC6(F)F)C
Molecular Formula
C27H26F2N8O3
Molecular Weight
548.54
References & Citations
[1]Zhou Ding, et al. uinazoline derivatives as antitumor agents. Patent. N112654612A
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
ErbB2/HER2

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