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Recombinant Human ERN1

CAT: 0013-GTR18893131-02Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18893131-02Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Recombinant Human ERN1
Product Name Alternative
Endoplasmic reticulum (ER) to nucleus signalling 1, Endoplasmic reticulum to nucleus signaling 1, Endoplasmic reticulum-to-nucleus signaling 1, Endoribonuclease, ER to nucleus signaling 1, ERN 1, Ern1, ERN1_HUMAN, hIRE 1p, hIRE1p, Inositol requiring 1, Inositol requiring 1, S. cerevisiae, homolog of, Inositol requiring enzyme 1, S. cerevisiae, homolog of, Inositol requiring protein 1
UniProt
O75460
Expression Region
465-663
Reactivity
Human
Tag
N-terminal His-IF2DI Tag
Source
E.Coli
Field of Research
Cell Biology
Purity
Greater than 90% by SDS-PAGE gel analyses
Molecular Weight
42.8 kDa
Storage Conditions
-20°C for 12 months as lyophilized;2-8°C for 1 month under sterile conditions after reconstitution
Notes
For research use only.
Applications Notes
Centrifuge the vial at 10,000 rpm for 1 minute, reconstitute at 200 μg/ml in sterile distilled water by gentle pipetting 2-3 times, don’t vortex
Tested Applications
ELISA, WB
Preservative
Lyophilized from a 0.2 μm filtered solution in PBS with 5% trehalose, pH 7.4

UniProtKB · O75460

Serine/threonine-protein kinase/endoribonuclease IRE1

ERN1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O75460
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ERN1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A1L457, A8K8N8, A8MXS7, Q59EE2
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

ADP-ribosylationDisulfide bondGlycoproteinPhosphoprotein

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisTranscriptionTranscription regulationUnfolded protein response

Ligand

ATP-bindingMagnesiumMetal-bindingNucleotide-binding

Cellular component

Endoplasmic reticulumMembrane

Molecular function

HydrolaseKinaseMultifunctional enzymeSerine/threonine-protein kinaseTransferase

Domain

SignalTransmembraneTransmembrane helix

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