Products for Research Use Only

Alpha-CGRP (8-37) Rat peptide

CAT: 0013-GTR18896249-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR18896249-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Alpha-CGRP (8-37) Rat peptide
Product Name Alternative
Calcitonin Gene-Related Peptide I (8-37) (mouse, rat), CGRP-I (8-37) (mouse, rat)
Source
Synthetic
Purity
> 95%
Form
Lyophilized powder
Molecular Weight
3127.58
Storage Conditions
Shipped at 4°C. Store at -20°C for one year.
Notes
For research use only.
Applications Notes
Alpha-CGRP (8-37), a competitive CGRP1 receptor antagonist, exhibited hypothermic and antinociceptive effects. CGRP-I (8-37) antagonized the effects of amylin and amylin (1-8) on osteoblasts but was substantially less potent in this regard than amylin (8-37) . Furthermore, it inhibited the evoked discharge frequency of wide dynamic range neurons in dorsal horn of the spinal cord in rats.
AA Sequence
H-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asp-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Glu-Ala-Phe-NH2