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Zaltidine

CAT: 0804-HY-15541-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-15541-01Size:5 mg
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Description
Zaltidine dihydrochloride (CP-5736 dihydrochloride) is a highly specific H2 receptor antagonist with antisecretion activity. Zaltidine dihydrochloride reduces the stimulant effect of histamine on gastric acid secretion by binding to histamine H2 receptors on gastric parietal cells, thus reducing gastric acid production. Zaltidine dihydrochloride can be used in the study of gastric acid-related diseases such as duodenal ulcers[1].
CAS Number
85604-00-8
Product Name Alternative
CP-57361
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/zaltidine.html
Purity
99.49
Solubility
10 mM in DMSO|H2O : 7.69 mg/mL (ultrasonic)
Smiles
NC(NC1=NC(C2=CN=C(C)N2)=CS1)=N
Molecular Formula
C8H10N6S
Molecular Weight
222.27
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Laferla G, Buchanan N, Hearns J, The antisecretory effects of zaltidine, a novel long-acting H2-receptor antagonist, in healthy volunteers and in subjects with a past history of duodenal ulcer. Br J Clin Pharmacol. 1986 Oct;22 (4) :395-9.|[2]Farup PG. Zaltidine: an effective but hepatotoxic H2-receptor antagonist. Scand J Gastroenterol. 1988 Aug;23 (6) :655-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
H2 Receptor

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