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Human HtrA2 protein

CAT: 0013-GTR18886876-01Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18886876-01Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Recombinant human HtrA2 protein
Product Name Alternative
High temperature requirement protein A2, HTRA 2, HtrA like serine protease, HtrA serine peptidase 2, HtrA, E. coli, homolog of, 2, HtrA2, HTRA2_HUMAN, mitochondrial, Omi stress regulated endoprotease, Omi stress-regulated endoprotease, PARK 13, PARK13, Protease serine 25, PRSS 25, PRSS25, Serine protease 25, Serine protease HTRA2, Serine protease HTRA2 mitochondrial
UniProt
O43464
Expression Region
133-358
Reactivity
Human
Tag
N-terminal His Tag or N-terminal His-IF2DI Tag, determined during production process
Source
E.Coli
Field of Research
Cell Biology
Purity
Greater than 95% as determined by SDS-PAGE
Molecular Weight
24.8 kDa
Storage Conditions
-20°C for 12 months as lyophilized;2-8°C for 1 month under sterile conditions after reconstitution
Notes
For research use only.
Applications Notes
Centrifuge the vial at 10,000 rpm for 1 minute, reconstitute at 200 μg/ml in sterile distilled water by gentle pipetting 2-3 times, don’t vortex
Tested Applications
ELISA, WB
Preservative
Lyophilized from a 0.2 μm filtered solution in 10 mM Hepes, 500 mM NaCl with 5% trehalose, pH 7.4

UniProtKB · O43464

Serine protease HTRA2, mitochondrial

HTRA2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O43464
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
HTRA2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.21.108
Processing
Precursor
Secondary accessions
Q9HBZ4, Q9P0Y3, Q9P0Y4
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Apoptosis

PTM

Autocatalytic cleavageUbl conjugationZymogen

Disease

Disease variantEpilepsyNeurodegenerationParkinson diseaseParkinsonism

Cellular component

Endoplasmic reticulumMembraneMitochondrion

Molecular function

HydrolaseProteaseSerine protease

Domain

Transit peptideTransmembraneTransmembrane helix

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