2-Phenyl-2-(1-piperidinyl)propane
CAT:
804-HY-W040468-01
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
2-Phenyl-2-(1-piperidinyl)propane
- CAS Number: 92321-29-4
- UNSPSC Description: 2-Phenyl-2-(1-piperidinyl)propane is a selective and reversible human CYP2B6 inhibitor with an IC50 of 5.1 μM and a Ki of 5.6. 2-Phenyl-2-(1-piperidinyl)propane inhibits CYP2D6 (IC50=74 μM), CYP3A (IC50=200 μM)[1].
- Target Antigen: Cytochrome P450
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Metabolism-sugar/lipid metabolism
- Field of Research: Metabolic Disease
- Assay Protocol: https://www.medchemexpress.com/2-phenyl-2-1-piperidinyl-propane.html
- Purity: 99.81
- Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: CC(N1CCCCC1)(C2=CC=CC=C2)C
- Molecular Weight: 203.329
- References & Citations: [1]Walsky RL, et al. A comparison of 2-phenyl-2-(1-piperidinyl)propane (ppp), 1,1',1''-phosphinothioylidynetrisaziridine (thioTEPA), clopidogrel, and ticlopidine as selective inactivators of human cytochrome P450 2B6. Drug Metab Dispos. 2007 Nov;35(11):2053-9.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, protect from light)
- Clinical Information: No Development Reported