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Human TARDBP protein

CAT: 0013-GTR18882732-01Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18882732-01Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This Human TARDBP protein spans the amino acid sequence from region 1-396aa. Purity: Greater than 90% as determined by SDS-PAGE.
Product Name Alternative
Short name, TDP-43
UniProt
Q13148
Expression Region
1-396aa
Tag
N-terminal 6xHis-tagged
Source
Yeast
Origin
Homo sapiens (Human)
Field of Research
Neuroscience
Purity
Greater than 90% as determined by SDS-PAGE.
Form
Liquid or Lyophilized powder
Molecular Weight
44.9 kDa
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
For research use only.
Applications Notes
N-terminal 6xHis-tagged: N-terminal 6xHis-tagged2-391AA: 1-396AAPartial : Partial
Preservative
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
AA Sequence
MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVKVKRAVQKTSDLIVLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIAQSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRFGGNPGGFGNQGGFGNSRGGGAGLGNNQGSNMGGGMNFGAFSINPAMMAAAQAALQSSWGMMGMLASQQNQSGPSGNNQNQGNMQREPNQAFGSGNNSYSGSNSGAAIGWGSASNAGSGSG

UniProtKB · Q13148

TAR DNA-binding protein 43

TADBP_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q13148
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TARDBP
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
TDP-43
EC number
—
Processing
—
Secondary accessions
A4GUK4, A4GUK5, A4GUK6, B2R629, B4DJ45, E2PU12, Q53H27, Q6FI92, Q96DJ0
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Disease

Amyotrophic lateral sclerosisDisease variantNeurodegeneration

Biological process

Biological rhythmsmRNA processingmRNA splicingTranscriptionTranscription regulation

Cellular component

CytoplasmMitochondrionNucleus

Molecular function

DNA-bindingRepressorRNA-binding

PTM

Isopeptide bondMethylationPhosphoproteinUbl conjugation

Domain

Repeat

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