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Human SIRT6 protein

CAT: 0013-GTR18882521-01Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18882521-01Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This Human SIRT6 protein spans the amino acid sequence from region 2-355aa. Purity: Greater than 90% as determined by SDS-PAGE.
Product Name Alternative
Regulatory protein SIR2 homolog 6 SIR2-like protein 6
UniProt
Q8N6T7
Expression Region
2-355aa
Tag
N-terminal GST-tagged
Source
E.coli
Origin
Homo sapiens (Human)
Field of Research
Cell Biology
Purity
Greater than 90% as determined by SDS-PAGE.
Form
Liquid or Lyophilized powder
Molecular Weight
66 kDa
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
For research use only.
Applications Notes
N-terminal GST-tagged: N-terminal GST-tagged1-397AA: 1-355AAFull Length of Isoform 2 : Full Length
Preservative
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
AA Sequence
SVNYAAGLSPYADKGKCGLPEIFDPPEELERKVWELARLVWQSSSVVFHTGAGISTASGIPDFRGPHGVWTMEERGLAPKFDTTFESARPTQTHMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKCKTQYVRDTVVGTMGLKATGRLCTVAKARGLRACRGELRDTILDWEDSLPDRDLALADEASRNADLSITLGTSLQIRPSGNLPLATKRRGGRLVIVNLQPTKHDRHADLRIHGYVDEVMTRLMKHLGLEIPAWDGPRVLERALPPLPRPPTPKLEPKEESPTRINGSIPAGPKQEPCAQHNGSEPASPKRERPTSPAPHRPPKRVKAKAVPS

UniProtKB · Q8N6T7

NAD-dependent protein deacylase sirtuin-6

SIR6_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8N6T7
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SIRT6
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.3.1.-
Processing
—
Secondary accessions
B2RCD0, O75291, Q6IAF5, Q6PK99, Q8NCD2, Q9BSI5, Q9BWP3, Q9NRC7, Q9UQD1
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Molecular function

AcyltransferaseChromatin regulatorDevelopmental proteinDNA-bindingGlycosyltransferaseNucleotidyltransferaseRNA-bindingTransferase

Coding sequence diversity

Alternative splicing

Cellular component

ChromosomeEndoplasmic reticulumNucleusTelomere

Biological process

DNA damageDNA repair

Ligand

Metal-bindingNADZinc

Disease

Tumor suppressor

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