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Human SIGLEC15 protein

CAT: 0013-GTR18882231-01Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18882231-01Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This Human SIGLEC15 protein spans the amino acid sequence from region 20-263aa. Purity: Greater than 90% as determined by SDS-PAGE.
Product Name Alternative
Sialic acid-binding Ig-like lectin 15; Siglec-15; CD33 antigen-like 3; SIGLEC15; CD33L3
UniProt
Q6ZMC9
Expression Region
20-263aa
Tag
N-terminal 6xHis-Myc-tagged
Source
Mammalian cell
Origin
Homo sapiens (Human)
Field of Research
Cancer Biology
Purity
Greater than 90% as determined by SDS-PAGE.
Bioactivity
Measured by its binding ability in a functional ELISA.Immobilized Human SIGLEC15 at 5 μg/mL can bind Anti-SIGLEC15 recombinant antibody. The EC50 is 12.42-16.08 ng/mL.
Form
Lyophilized powder
Molecular Weight
30.7 kDa
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
For research use only.
Applications Notes
Baculovirus and Mammalian Cell N-terminal 6xHis-tagged and Flag-tagged Full Length
Preservative
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
AA Sequence
FVRTKIDTTENLLNTEVHSSPAQRWSMQVPPEVSAEAGDAAVLPCTFTHPHRHYDGPLTAIWRAGEPYAGPQVFRCAAARGSELCQTALSLHGRFRLLGNPRRNDLSLRVERLALADDRRYFCRVEFAGDVHDRYESRHGVRLHVTAAPRIVNISVLPSPAHAFRALCTAEGEPPPALAWSGPALGNSLAAVRSPREGHGHLVTAELPALTHDGRYTCTAANSLGRSEASVYLFRFHGASGAST

UniProtKB · Q6ZMC9

Sialic acid-binding Ig-like lectin 15

SIG15_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q6ZMC9
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SIGLEC15
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Siglec-15
EC number
—
Processing
Precursor
Secondary accessions
A8K2Y5, B4DVQ9
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

PTM

Disulfide bondGlycoprotein

Domain

Immunoglobulin domainSignalTransmembraneTransmembrane helix

Cellular component

Membrane

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