Thymopentin (acetate)

• Description:

  Thymopentin acetate is a biologically active peptide secreted mainly by the epithelial cells of thymic cortex and medulla. Thymopentin acetate is an effective immunomodulatory agent with a short plasma half-life of 30 seconds. Thymopentin acetate enhances the generation of T-cell lineage derived from human embryonic stem cells (hESCs) [1][2].

• UNSPSC:

  12352209

• Target:

  Endogenous Metabolite

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/thymopentin-acetate.html

• Purity:

  99.95

• Solubility:

  DMSO : 25 mg/mL (ultrasonic) |H2O : 25 mg/mL (ultrasonic; heat to 60°C)

• Smiles:

  O=C (N[C@@H] (C (C) C) C (N[C@H] (C (O) =O) CC1=CC=C (O) C=C1) =O) [C@H] (CC (O) =O) NC ([C@H] (CCCCN) NC ([C@@H] (N) CCCNC (N) =N) =O) =O.CC (O) =O

• Molecular Formula:

  C32H53N9O11

• Molecular Weight:

  739.82

• References & Citations:

  [1]Zhu MX, et al. Thymopentin enhances the generation of T-cell lineage derived from human embryonic stem cells in vitro. Exp Cell Res. 2015 Feb 15;331 (2) :387-98.|[2]Lin S, et al. Novel strategy for immunomodulation: Dissolving microneedle array encapsulating thymopentin fabricated by modified two-step molding technology. Eur J Pharm Biopharm. 2018 Jan;122:104-112.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category:

  Natural Products

• Clinical Information:

  Launched

• CAS Number:

  89318-88-7