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Human MB21D1 protein

CAT: 0013-GTR18882059-01Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18882059-01Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This Human MB21D1 protein spans the amino acid sequence from region 161-522aa. Purity: Greater than 90% as determined by SDS-PAGE.
Product Name Alternative
Short name, cGAMP synthase Short name, cGAS Short name, h-cGAS Alternative name (s), 2'3'-cGAMP synthase Mab-21 domain-containing protein 1
UniProt
Q8N884
Expression Region
161-522aa
Tag
N-terminal 6xHis-SUMO-tagged
Source
E.coli
Origin
Homo sapiens (Human)
Field of Research
Infectious Disease & Virology
Purity
Greater than 90% as determined by SDS-PAGE.
Form
Liquid or Lyophilized powder
Molecular Weight
58.3 kDa
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
For research use only.
Applications Notes
E.coli and Yeast N-terminal 6xHis-SUMO-tagged Partial
Preservative
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
AA Sequence
GASKLRAVLEKLKLSRDDISTAAGMVKGVVDHLLLRLKCDSAFRGVGLLNTGSYYEHVKISAPNEFDVMFKLEVPRIQLEEYSNTRAYYFVKFKRNPKENPLSQFLEGEILSASKMLSKFRKIIKEEINDIKDTDVIMKRKRGGSPAVTLLISEKISVDITLALESKSSWPASTQEGLRIQNWLSAKVRKQLRLKPFYLVPKHAKEGNGFQEETWRLSFSHIEKEILNNHGKSKTCCENKEEKCCRKDCLKLMKYLLEQLKERFKDKKHLDKFSSYHVKTAFFHVCTQNPQDSQWDRKDLGLCFDNCVTYFLQCLRTEKLENYFIPEFNLFSSNLIDKRSKEFLTKQIEYERNNEFPVFDEF

UniProtKB · Q8N884

Cyclic GMP-AMP synthase

CGAS_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8N884
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CGAS
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
cGAMP synthase, cGAS, h-cGAS
EC number
2.7.7.86
Processing
—
Secondary accessions
L0L2J9, Q14CV6, Q32NC9, Q5SWL0, Q5SWL1, Q96E45
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationADP-ribosylationIsopeptide bondLipoproteinMethylationPalmitatePhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Biological process

Antiviral defenseDNA damageDNA repairHost-virus interactionImmunityInnate immunity

Ligand

ATP-bindingGTP-bindingLipid-bindingMagnesiumMetal-bindingNucleotide-bindingZinc

Cellular component

Cell membraneChromosomeCytoplasmMembraneNucleus

Molecular function

DNA-bindingNucleotidyltransferaseTransferase

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