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Human CYP11B2 protein

CAT: 0013-GTR18881875-01Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18881875-01Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This Human CYP11B2 protein spans the amino acid sequence from region 25-503. Purity: Greater than 90% as determined by SDS-PAGE.
Product Name Alternative
Aldosterone synthase (EC, 1.14.15.4, EC, 1.14.15.5) Short name, ALDOS Aldosterone-synthesizing enzyme CYPXIB2 Cytochrome P-450Aldo Cytochrome P-450C18 Steroid 18-hydroxylase
UniProt
P19099
Expression Region
25-503
Tag
N-terminal 6xHis-SUMO-tagged
Source
E.coli
Origin
Homo sapiens (Human)
Field of Research
Metabolism Research
Purity
Greater than 90% as determined by SDS-PAGE.
Form
Liquid or Lyophilized powder
Molecular Weight
71 kDa
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
For research use only.
Applications Notes
E.coli and Yeast N-terminal 6xHis-tagged Partial
Preservative
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
AA Sequence
GTRAARAPRTVLPFEAMPQHPGNRWLRLLQIWREQGYEHLHLEMHQTFQELGPIFRYNLGGPRMVCVMLPEDVEKLQQVDSLHPCRMILEPWVAYRQHRGHKCGVFLLNGPEWRFNRLRLNPDVLSPKAVQRFLPMVDAVARDFSQALKKKVLQNARGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFMPRSLSRWISPKVWKEHFEAWDCIFQYGDNCIQKIYQELAFNRPQHYTGIVAELLLKAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHPQKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLGRNAALFPRPERYNPQRWLDIRGSGRNFHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFLVETLTQEDIKMVYSFILRPGTSPLLTFRAIN

UniProtKB · P19099

Cytochrome P450 11B2, mitochondrial

C11B2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P19099
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CYP11B2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B0ZBE4, Q16726
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Disease

Disease variant

Ligand

HemeIronMetal-binding

Biological process

Lipid metabolismSteroid metabolismSteroidogenesis

Cellular component

MembraneMitochondrionMitochondrion inner membrane

Molecular function

MonooxygenaseOxidoreductase

Domain

Transit peptide

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