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BRD9757

CAT: 0804-HY-117554-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-117554-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BRD9757 is a potent, capless and selective HDAC6 inhibitor with an IC50 of 30 nM. BRD9757 shows excellent selectivity toward HDAC6 versus the class I (>20-fold) and class II (>400-fold) HDACs[1].
CAS Number
[1423058-85-8]
Product Name Alternative
1α,25-Dihydroxy-3-epi-vitamin-D3
UNSPSC
12352211
Hazard Statement
H319, H412
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/brd9757.html
Purity
99.75
Solubility
H2O : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=CCCC1)NO
Molecular Formula
C6H9NO2
Molecular Weight
127.14
Precautions
H319, H412
References & Citations
[1]Florence F Wagner, et al. Potent and selective inhibition of histone deacetylase 6 (HDAC6) does not require a surface-binding motif. J Med Chem. 2013 Feb 28;56 (4) :1772-6.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC1; HDAC2; HDAC3; HDAC4; HDAC5; HDAC6; HDAC7; HDAC8; HDAC9

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