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Human SETDB1 protein

CAT: 0013-GTR18882520-01Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18882520-01Size:20 µg
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Description
This Human SETDB1 protein spans the amino acid sequence from region 1-397aa. Purity: Greater than 90% as determined by SDS-PAGE.
Product Name Alternative
ERG-associated protein with SET domain
UniProt
Q15047
Expression Region
1-397aa
Tag
N-terminal GST-tagged
Source
E.coli
Origin
Homo sapiens (Human)
Field of Research
Epigenetics & Chromatin
Purity
Greater than 90% as determined by SDS-PAGE.
Form
Liquid or Lyophilized powder
Molecular Weight
71.7 kDa
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
For research use only.
Applications Notes
N-terminal GST-tagged: N-terminal GST-tagged1-351AA: 1-397AAFull Length : Full Length of Isoform 2
Preservative
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
AA Sequence
MSSLPGCIGLDAATATVESEEIAELQQAVVEELGISMEELRHFIDEELEKMDCVQQRKKQLAELETWVIQKESEVAHVDQLFDDASRAVTNCESLVKDFYSKLGLQYRDSSSEDESSRPTEIIEIPDEDDDVLSIDSGDAGSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSSQDLHKGTLSQMSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPGKKYKVKFDNKGKSLLSGNHIAYDYHPPADKLYVGSRVVAKYKDGNQVWLYAGIVAETPNVKNKLRFLIFFDDGYASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAYPNRPMVLLKSGQLIKTEWEGTWWKSRVEEVDGSLVRILFLVLFFSTILEAEVGGGGT

UniProtKB · Q15047

Histone-lysine N-methyltransferase SETDB1

SETB1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q15047
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SETDB1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.1.1.366
Processing
—
Secondary accessions
A6NEW2, Q5SZD8, Q5SZD9, Q5SZE0, Q5SZE7, Q96GM9
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Molecular function

Chromatin regulatorMethyltransferaseRepressorTransferase

Cellular component

ChromosomeCytoplasmNucleus

Domain

Coiled coilRepeat

PTM

Isopeptide bondMethylationPhosphoproteinUbl conjugation

Ligand

Metal-bindingS-adenosyl-L-methionineZinc

Biological process

TranscriptionTranscription regulation

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