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Human CYP21A2 protein

CAT: 0013-GTR18880951-01Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18880951-01Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This Human CYP21A2 protein spans the amino acid sequence from region 1-494a. Purity: Greater than 90% as determined by SDS-PAGE.
Product Name Alternative
CYP21A2
UniProt
P08686
Expression Region
1-494a
Tag
N-terminal 6xHis-tagged
Source
E.coli
Origin
Homo sapiens (Human)
Field of Research
Metabolism Research
Purity
Greater than 90% as determined by SDS-PAGE.
Form
Liquid or Lyophilized powder
Molecular Weight
59.9 kDa
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
For research use only.
Applications Notes
Full length of His-tag and expression region is 1-494a
Preservative
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
AA Sequence
MLLLGLLLLPLLAGARLLWNWWKLRSLHLPPLAPGFLHLLQPDLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSKNYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTCSIICYLTFGDKIKDDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFFPNPGLRRLKQAIEKRDHIVEMQLRQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALPSLQPLPHCSVILKMQPFQVRLQPRGMGAHSPGQNQ

UniProtKB · P08686

Steroid 21-hydroxylase

CP21A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P08686
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CYP21A2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
1.14.14.16
Processing
—
Secondary accessions
A2BHY6, P04033, Q01204, Q08AG8, Q16749, Q16806, Q16874, Q5ST44, Q96NU8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Disease

Congenital adrenal hyperplasiaDisease variant

Cellular component

Endoplasmic reticulumMembraneMicrosome

Ligand

HemeIronLipid-bindingMetal-bindingSteroid-binding

Biological process

Lipid metabolismSteroidogenesis

Molecular function

MonooxygenaseOxidoreductase

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