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FTase

CAT: 0013-GTR18878155Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18878155Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FTase catalyzes the transfer of the farnesyl group from farnesyl diphosphate to proteins containing a C-terminal CaaX motif, where 'C' is a conserved cysteine that is the site of farnesyl modification, 'a' is usually an aliphatic amino acid, and 'X' is methionine, serine, glutamine, or alanine.
Product Name Alternative
Protein farnesyltransferase, α- and β-subunit, rat, recombinant, E. coli
Source
E. coli
Origin
Rat
Purity
> 90% (SDS-PAGE)
Bioactivity
1 pmol of FTase will transfer 1 pmol of farnesyl to H-Ras in 15 min at 37°C.
Form
Liquid (Supplied in 25 mM HEPES pH 7.2, 40 mM NaCl, 1 mM TCEP and 10 μM ZnSO 4)
Molecular Weight
Theoretical MW: α: 44 kDa, β: 49 kDa
Storage Conditions
Store at -80 °C. Ships on dry ice.
Notes
For research use only.
Applications Notes
Activity: 1 pmol of GGTase-I will transfer 5 pmol of Farnesyl to RhoA in 15 min at 37°C.

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