Products for Research Use Only
RegisterLogin

S16–1029

CAT: 0804-HY-161331Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-161331Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
S16–1029 is a selective and orally active butyrylcholinesterase (BChE) inhibitor with IC50s of 11.35 nM and 48.1 nM for eqBChE and hBChE, respectively. S16–1029 could cross the blood-brain barrier (BBB) and reach the central nervous system (CNS) . S16–1029 can be used for Alzheimer's disease (AD) research[1].
CAS Number
2653349-51-8
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/s16-1029.html
Solubility
10 mM in DMSO
Smiles
O=C(CN1C(C2=NON=C2N)=NC3=C1C=CC=C3)NC4=CC=C(CCN5CCOCC5)C=C4
Molecular Formula
C23H25N7O3
Molecular Weight
447.49
References & Citations
[1]Shuaishuai Xing, et al. Optimizing drug-like properties of selective butyrylcholinesterase inhibitors for cognitive improvement: Enhancing aqueous solubility by disrupting molecular plane. Eur J Med Chem. 2024 Mar 2:268:116289.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
BChE

Related Products

CatalogName
HY-112391SD-1029
HY-123787MK-1029
HY-161043ECDD-S16
HY-P87030Phospho-Phospholamban (S16) Antibody (YA6723, Rabbit)
HY-P991386PM-1021
HY-147384CXL-1020
HY-115359BL-1021
HY-13962-01SGI-1027
HY-132298-01TDI-10229
HY-103459CI-1020

Alternative Products

CatalogName
GTR19234678-01S16–1029
MBS5774519SD-1029
MBS3600979MK-1029
GTR19195065-01CI-1029
PX-P4283-01Genome polyprotein (691-1029)
E53M01161CD45 (1029-1249aa) Monoclonal Antibody
sc-221773JAK2 Inhibitor III, SD-1029
GTR19261658-01ECDD-S16
324408-01MRP-S16
12-9092-50Anti-TNFRSF10B Antibody (tigatuzumab biosimilar) (GEN-1029)

Popular Products