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Cav2.2 rabbit pAb

CAT: 0855-ES20796-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES20796-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Calcium voltage-gated channel subunit alpha1 B (CACNA1B) Homo sapiens The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Description
Calcium voltage-gated channel subunit alpha1 B (CACNA1B) Homo sapiens The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011],
UniProt
Q00975
Swiss Prot
Q00975
Reactivity
Human; Rat; Mouse
Immunogen
Synthetic Peptide of Cav2.2 AA range: 230-310
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF
Concentration
1 mg/ml
Dilution
IHC 1:50-100
Molecular Weight
263kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
263kD
Fragment
IgG
Subcellular Location
Membrane ; Multi-pass membrane protein .
Other Product Names
Voltage-dependent N-type calcium channel subunit alpha-1B (Brain calcium channel III; BIII; Calcium channel, L type, alpha-1 polypeptide isoform 5; Voltage-gated calcium channel subunit alpha Cav2.2)
Gene ID (Human)
774

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