Products for Research Use Only
RegisterLogin

Lenacapavir

CAT: 0804-HY-111964-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-111964-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Lenacapavir (GS-6207) is a HIV-1 capsid inhibitor. Lenacapavir shows anti-HIV activity with an EC50 of 100 pM in MT-4 cells. Lenacapavir displays a mean EC50 of 50 pM (20-160 pM) against 23 HIV-1 clinical isolates from different subtypes in peripheral blood mononuclear cells (PBMCs) [1]. Lenacapavir is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
2189684-44-2
Product Name Alternative
GS-6207
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
HIV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/gs-6207.html
Concentration
10mM
Purity
98.44
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
FC1=CC(F)=CC(C[C@@H](C2=NC(C#CC(S(=O)(C)=O)(C)C)=CC=C2C3=CC=C(Cl)C4=C3N(CC(F)(F)F)N=C4NS(=O)(C)=O)NC(CN5C(C(F)(F)[C@@]6([H])[C@]7([H])C6)=C7C(C(F)(F)F)=N5)=O)=C1
Molecular Formula
C39H32ClF10N7O5S2
Molecular Weight
968.28
Precautions
H315, H319, H320
References & Citations
[1]Singh K, et al. GS-CA Compounds: First-In-Class HIV-1 Capsid Inhibitors Covering Multiple Grounds. Front Microbiol. 2019 Jun 20;10:1227.|[2]John O Link, et al. Clinical targeting of HIV capsid protein with a long-acting small molecule. Nature. 2020 Jul 1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
HIV-1

Alternative Products

CatalogName
AL180739-01Lenacapavir
L329079Lenacapavir-D3
GTR19241639-01Lenacapavir sodium
T211724-01Lenacapavir pacfosacil
TRC-L207061-25MGLenacapavir-D5
CS-O-59250Lenacapavir-d6
RM-L213111-01Lenacapavir Impurity 11
RM-L213110-01Lenacapavir Impurity 10
RM-L213109-01Lenacapavir Impurity 9
RM-L213104-01Lenacapavir Impurity 4

Popular Products