Azidoethyl-SS-ethylamine
CAT:
804-HY-140104-02
Size:
50 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Azidoethyl-SS-ethylamine
- CAS Number: 1807512-40-8
- UNSPSC Description: Azidoethyl-SS-ethylamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azidoethyl-SS-ethylamine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Target Antigen: ADC Linker
- Type: ADC Related
- Related Pathways: Antibody-drug Conjugate/ADC Related
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/azidoethyl-ss-ethylamine.html
- Solubility: DMSO : 250 mg/mL (ultrasonic)
- Smiles: NCCSSCCN=[N+]=[N-]
- Molecular Weight: 178.28
- References & Citations: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
- Shipping Conditions: Blue Ice
- Clinical Information: No Development Reported