Interferon-lambda1 (Interleukin-29)

• Description:

  Interferon-lambda1 (Interleukin-29)_x000D_ Catalog number: B2010307_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Volume/Weight: 10 ug_x000D_ pH: 7.4 upon reconstitution_x000D_ Supplied as: Lyophilized Powder_x000D_ Appearance: Powder_x000D_ Applications: highly pure Interferon-lambda1 (Interleukin-29) expressed in E. coli. This protein acts as a member of the interferon lambda family, with immunoregulatory, antiviral, anti-proliferative, and antitumor properties._x000D_ Storage: -20C_x000D_ Keywords: rHuIFN-λ1/IL-29; IL-29; IFN-lambda-1; Cytokine Zcyto21; Interleukin-29_x000D_ Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Liu S, Fang P, Ke W, Wang J, Wang X, Xiao S, Fang L. Porcine deltacoronavirus_x000D_ (PDCoV) infection antagonizes interferon-λ1 production. Vet Microbiol. 2020_x000D_ Aug;247:108785._x000D_ _x000D_ 2: Chen Y, Wang Y, Tang R, Yang J, Dou C, Dong Y, Sun D, Zhang C, Zhang L, Tang_x000D_ Y, Dai Q, Luo F, Xu J, Dong S. Dendritic cells-derived interferon-λ1 ameliorated_x000D_ inflammatory bone destruction through inhibiting osteoclastogenesis. Cell Death_x000D_ Dis. 2020 Jun 2;11(6):414._x000D_ _x000D_ 3: Yuan WM, Zhang R, Zhang Q, Ma FL, Wang C, Wang YZ, Zeng Y, Zheng LS. The_x000D_ generation and biological activity of a long-lasting recombinant human_x000D_ interferon-λ1. Protein Eng Des Sel. 2018 Sep 1;31(9):355-360._x000D_ _x000D_ 4: Gao D, Zhao J, Li X, Xia Y, Cai Y, Pan J, Zhou H, Fang Y, Zhang S, Wen H._x000D_ Interferon-λ1 suppresses invasion and enhances autophagy in human osteosarcoma_x000D_ cell. Int J Clin Exp Med. 2015 Sep 15;8(9):14999-5004._x000D_ _x000D_ 5: Chrysanthopoulou A, Kambas K, Stakos D, Mitroulis I, Mitsios A, Vidali V,_x000D_ Angelidou I, Bochenek M, Arelaki S, Arampatzioglou A, Galani IE, Skendros P,_x000D_ Couladouros EA, Konstantinides S, Andreakos E, Schäfer K, Ritis K. Interferon_x000D_ lambda1/IL-29 and inorganic polyphosphate are novel regulators of neutrophil-_x000D_ driven thromboinflammation. J Pathol. 2017 Sep;243(1):111-122._x000D_ _x000D_ 6: Zhang L, Li W, Sun Y, Li X, Kong L, Xu P, Xia P, Yue J. Activation of_x000D_ activating Fc gamma receptors down-regulates the levels of interferon β,_x000D_ interferon γ and interferon λ1 in porcine alveolar macrophages during PRRSV_x000D_ infection. Int Immunopharmacol. 2020 Apr;81:106268._x000D_ _x000D_ 7: Hsu YL, Wang MY, Ho LJ, Lai JH. Dengue virus infection induces interferon-_x000D_ lambda1 to facilitate cell migration. Sci Rep. 2016 Jul 26;6:24530._x000D_ _x000D_ 8: Gielen V, Johnston SL, Edwards MR. Azithromycin induces anti-viral responses_x000D_ in bronchial epithelial cells. Eur Respir J. 2010 Sep;36(3):646-54._x000D_ _x000D_ 9: Liu D, Chang CH, Rossi EA, Cardillo TM, Goldenberg DM. Interferon-λ1 linked_x000D_ to a stabilized dimer of Fab potently enhances both antitumor and antiviral_x000D_ activities in targeted cells. PLoS One. 2013 May 16;8(5):e63940._x000D_ _x000D_ 10: Chang CY, Liu HM, Chang MF, Chang SC. Middle East Respiratory Syndrome_x000D_ Coronavirus Nucleocapsid Protein Suppresses Type I and Type III Interferon_x000D_ Induction by Targeting RIG-I Signaling. J Virol. 2020 Jun 16;94(13):e00099-20._x000D_ _x000D_ Products Related to Interferon-lambda1 (Interleukin-29) : Proteins

• Short Description:

  Catalog Number: B2010307 (10 ug)_x000D_ Interferon-lambda1 (Interleukin-29) is a high quality research product used as highly pure Interferon-lambda1 (Interleukin-29) expressed in E. coli. This protein acts as a member of the interferon lambda family, with immunoregulatory, antiviral, anti-proliferative, and antitumor properties. Custom bulk orders of this product are available upon request.

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5