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Mipasetamab

CAT: 0804-HY-P99733-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P99733-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mipasetamab is an IgG1κ antibody targeting to AXL, a tyrosine kinase receptor and an TAM Receptor. Mipasetamab involves in synthesis of ADCT-601 (Mipasetamab uzoptirine), an AXL-targeted antibody-drug conjugate (ADC) . ADCT-601 has anti-tumor activity[1].
CAS Number
2361055-48-1
UNSPSC
12352203
Target
ADC Antibody; TAM Receptor
Type
Inhibitory Antibodies
Related Pathways
Antibody-drug Conjugate/ADC Related; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mipasetamab.html
Purity
98.26
Solubility
10 mM in DMSO
Smiles
[Mipasetamab]
Molecular Weight
(145.6 kDa)
References & Citations
[1]Zammarchi F, et al. Preclinical Development of ADCT-601, a Novel Pyrrolobenzodiazepine Dimer-based Antibody-drug Conjugate Targeting AXL-expressing Cancers. Mol Cancer Ther. 2022 Apr 1;21 (4) :582-593.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
Isoform
Axl

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