Products for Research Use Only
RegisterLogin

Oxazolone

CAT: 0804-HY-126360-01Size: 500 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-126360-01Size:500 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Oxazolone is a haptenizing agent that induces acute or chronic inflammation of the large intestine and is used to construct models of colitis. Oxazolone can cause Th1/Th2-dependent colitis with weight loss and diarrhea. Oxazolone-induced inflammation can be mitigated by neutralizing anti-IL-4 or anti-TNF-α antibodies or decoy IL-13R2-α-FC proteins[1].
CAS Number
15646-46-5
UNSPSC
12352005
Hazard Statement
H317
Target
Interleukin Related; TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/oxazolone.html
Purity
98.0
Solubility
50% Ethanol in Water : 10 mg/mL (ultrasonic) |DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(OC(C1=CC=CC=C1)=N/2)C2=C/OCC
Molecular Formula
C12H11NO3
Molecular Weight
217.22
Precautions
H317
References & Citations
[1]Weigmann B, et al. Oxazolone-Induced Colitis as a Model of Th2 Immune Responses in the Intestinal Mucosa. Methods Mol Biol. 2016;1422:253-61.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IL-13; IL-4; TNFRSF1A/CD120a

Related Products

CatalogName
HY-156231Glc-GIcNAc-oxazoline
HY-34631-01Oxazole
HY-117445Oxazole yellow
HY-D1245Oxazole blue
HY-180467Neu5Ac-2Galβ1-3Glc-oxazoline- (2) Me
HY-41882-01(S) -4-Benzyl-2-oxazolidone
HY-69111-01Ethyl oxazole-4-carboxylate
HY-114521-015- (4-Methoxyphenyl) oxazole
HY-I0127R-015-Chloro-2- (5-methyl-1,4-diazepan-1-yl) benzo[d]oxazole (Standard)

Alternative Products

CatalogName
MBS3609863-01Oxazolone
419006-012-Oxazolone
BAA199012-Phenyl-5-oxazolone
D4925734,5-Diphenyl-2(3H)-oxazolone
sc-2670924- (4-Chlorobenzylidene) -2-methyl-5-oxazolone
D3440-104- (3,4-Diacetoxybenzal) -2-methyl-5-oxazolone
D3068754-(3,4-Diacetoxybenzal)-2-methyl-5-oxazolone
abx185246-015(4H)-Oxazolone,2-ethenyl-4,4-dimethyl-
OR3108372-Methyl-4- (3-pyridinylmethylene) -5 (4H) -oxazolone
sc-2671024- (4-Methanesulfonyl-benzylidene) -2-methyl-5-oxazolone

Popular Products