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Acremonidin A

CAT: 0804-HY-N10198Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N10198Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Acremonidin A is a potent calmodulin (CaM) inhibitor found in Purpureocillium lilacinum. Acremonidin A binds to the human calmodulin (hCaM) biosensor hCaM M124C-mBBr, with Kd of 19.40 nM[1].
CAS Number
701914-77-4
UNSPSC
12352005
Target
Calmodulin; Endogenous Metabolite
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/acremonidin-a.html
Solubility
10 mM in DMSO
Smiles
CC(O[C@@H](C1=CC(C)=CC(O)=C21)[C@](CC(C3=C4O)=CC(O)=C4C(C(C(O)=CC=C5O)=C5C(OC)=O)=O)(C=C[C@]3([H])C6=O)C6=C2O)=O
Molecular Formula
C33H26O12
Molecular Weight
614.55
References & Citations
[1]Madariaga-Mazón A, et al. Absolute configuration of acremoxanthone C, a potent calmodulin inhibitor from Purpureocillium lilacinum. J Nat Prod. 2013;76 (8) :1454-1460.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Microbial Metabolite

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CatalogName
MBS5815152Acremonidin A

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