Human Interferon-alpha2a (Highly Pure)

• Description:

  Human Interferon-alpha2a (Highly Pure)_x000D_ Catalog number: B2010282_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Volume/Weight: 10 ug_x000D_ pH: 7.4 upon reconstitution_x000D_ Supplied as: Lyophilized Powder_x000D_ Appearance: Powder_x000D_ Applications: highly pure Human Interferon-alpha2a (Highly Pure) expressed in E. coli. This protein acts as a regulatory mediator of the immune response with demonstrated antiviral and antitumor activities._x000D_ Storage: -20C_x000D_ Keywords: rHuIFN-α2a; IFNA; IFNA2; IFN-a 2a_x000D_ Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Eigentler TK, Gutzmer R, Hauschild A, Heinzerling L, Schadendorf D, Nashan D,_x000D_ Hölzle E, Kiecker F, Becker J, Sunderkötter C, Moll I, Richtig E, Pönitzsch I,_x000D_ Pehamberger H, Kaufmann R, Pföhler C, Vogt T, Berking C, Praxmarer M, Garbe C;_x000D_ Dermatologic Cooperative Oncology Group (DeCOG). Adjuvant treatment with_x000D_ pegylated interferon α-2a versus low-dose interferon α-2a in patients with high-_x000D_ risk melanoma: a randomized phase III DeCOG trial. Ann Oncol. 2016_x000D_ Aug;27(8):1625-32._x000D_ _x000D_ 2: Ma Y, Bao X, Xiong F, Wang J, Gu N, Guo J, Wu H, Lu J. The effect of_x000D_ thymopentin add-on in hepatitis B e antigen positive chronic hepatitis B after_x000D_ virus suppression by peginterferon plus entecavir therapy. Cell Mol Biol (Noisy-_x000D_ le-grand). 2019 Feb 28;65(2):75-81._x000D_ _x000D_ 3: Aruna, Li L. Anti-Interferon Alpha Antibodies in Patients with High-Risk_x000D_ BCR/ABL-Negative Myeloproliferative Neoplasms Treated with Recombinant Human_x000D_ Interferon-α. Med Sci Monit. 2018 Apr 17;24:2302-2309._x000D_ _x000D_ 4: Dou Y, van Montfoort N, van den Bosch A, Janssen HLA, de Man RA, Buschow SI,_x000D_ Woltman AM. Elevated serum levels of soluble CD14 in HBeAg-positive chronic HBV_x000D_ patients upon Peginterferon treatment are associated with treatment response. J_x000D_ Viral Hepat. 2019 Sep;26(9):1076-1085._x000D_ _x000D_ 5: Covic A, Maftei ID, Mardare NG, Ioniţă-Radu F, Totolici C, Tuţă L, Golea O,_x000D_ Covic M, Volovăţ C, Gusbeth-Tatomir P, Mircescu G. Analysis of safety and_x000D_ efficacy of pegylated-interferon alpha-2a in hepatitis C virus positive_x000D_ hemodialysis patients: results from a large, multicenter audit. J Nephrol. 2006_x000D_ Nov-Dec;19(6):794-801._x000D_ _x000D_ 6: Masci P, Bukowski RM, Patten PA, Osborn BL, Borden EC. New and modified_x000D_ interferon alfas: preclinical and clinical data. Curr Oncol Rep. 2003_x000D_ Mar;5(2):108-13._x000D_ _x000D_ 7: Motzer RJ, Schwartz L, Law TM, Murphy BA, Hoffman AD, Albino AP, Vlamis V,_x000D_ Nanus DM. Interferon alfa-2a and 13-cis-retinoic acid in renal cell carcinoma:_x000D_ antitumor activity in a phase II trial and interactions in vitro. J Clin Oncol._x000D_ 1995 Aug;13(8):1950-7._x000D_ 8: Zhang YL, Zhang J, Cui LY. Interferon-α combined with lamivudine versus_x000D_ lamivudine monotherapy for the emergence of YMDD mutations in chronic hepatitis_x000D_ B infection: a meta-analysis of randomized controlled trials._x000D_ Hepatogastroenterology. 2015 Jan-Feb;62(137):133-9. PMID: 25911883._x000D_ _x000D_ Products Related to Human Interferon-alpha2a (Highly Pure) : Proteins

• Short Description:

  Catalog Number: B2010282 (10 ug)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5