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Eleutherin

CAT: 0804-HY-N8248-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N8248-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Eleutherin is a type of naphthoquinone derivative with the protective effect against the injury ofhuman umbilical vein endothelial cells (HUVECs), which can be isolated from the edible bulbs of Eleutherine americana (Hong-Cong) [1].
CAS Number
478-36-4
Product Name Alternative
(+) -Eleutherin
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Topoisomerase
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/eleutherin.html
Purity
99.22
Solubility
DMSO : 14.29 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=C2[C@@H](C)O[C@@H](C)C1)C3=C(C2=O)C(OC)=CC=C3
Molecular Formula
C16H16O4
Molecular Weight
272.30
Precautions
H302, H315, H319, H335
References & Citations
[1]Castro ALG, et, al. Evaluation of the genotoxicity and mutagenicity of isoeleutherin and eleutherin isolated from Eleutherine plicata herb. using bioassays and in silico approaches. Arabian Journal of Chemistry. Volume 14, Issue 4, April 2021, 103084.|[2]Krishnan P, et, al. Novel mechanisms of DNA topoisomerase II inhibition by pyranonaphthoquinone derivatives-eleutherin, alpha lapachone, and beta lapachone. Biochem Pharmacol. 2000 Nov 1;60 (9) :1367-79.|[3]Chen D, et al. New naphtoquinones derivatives from the edible bulbs of Eleutherine americana and their protective effect on the injury of human umbilical vein endothelial cells. Fitoterapia. 2019 Jan;132:46-52.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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