TEPC466

• Description :

  TEPC466 is a novel TEPP-46-based aggregation-induced emission (AIE) probe. TEPC466 shows a high degree of selectivity and sensitivity for the detection of PKM2 protein via the AIE effect. EPC466 can be used for the detection of PKM2. TEPC466 is successfully applied in imaging the PKM2 protein in colorectal cancer cells with low toxicity. TEPC466 is a useful tool for cancer diagnosis and research[1].

• CAS Number :

  [2621957-88-6]

• UNSPSC :

  12171500

• Target :

  Pyruvate Kinase

• Type :

  Dye Reagents

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/tepc466.html

• Purity :

  99.92

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1N(N=CC2=C1N(C)C3=C2SC(S(C)=O)=C3)CC4=CC=CC(NC(C5=CC6=CC=CC=C6OC5=O)=O)=C4

• Molecular Formula :

  C27H20N4O5S2

• Molecular Weight :

  544.60

• References & Citations :

  [1]Wang D, et al. TEPP-46-Based AIE Fluorescent Probe for Detection and Bioimaging of PKM2 in Living Cells. Anal Chem. 2021;93 (37) :12682-12689.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Dye Reagents

• Clinical Information :

  No Development Reported