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N-Acetyllactosamine

CAT: 0804-HY-126854-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-126854-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
N-Acetyllactosamine (N-Acetyl-D-lactosamine), a nitrogen-containing disaccharide, is a galectin-3 inhibitor, which is an important component of various oligosaccharides such as glycoproteins and sialyl Lewis X. N-Acetyllactosamine can be used as the starting material for the synthesis of various oligosaccharides. N-Acetyllactosamine has prebiotic effects[1][2][3][4].
CAS Number
32181-59-2
Product Name Alternative
N-Acetyl-D-lactosamine
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; Galectin
Type
Natural Products
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/n-acetyllactosamine.html
Purity
99.95
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
O=C[C@H](NC(C)=O)[C@H]([C@@H]([C@@H](CO)O)O[C@H]1[C@@H]([C@H]([C@H]([C@@H](CO)O1)O)O)O)O
Molecular Formula
C14H25NO11
Molecular Weight
383.35
Precautions
H302, H315, H319, H335
References & Citations
[1]Endo T, Koizumi S, Tabata K, Kakita S, Ozaki A. Large-scale production of N-acetyllactosamine through bacterial coupling. Carbohydr Res. 1999 Mar 31;316 (1-4) :179-83.|[2]M.Karimi Alavijeh, et al. Simulation and economic assessment of large-scale enzymatic N-acetyllactosamine manufacture. Biochemical Engineering Journal. Volume 154, 15 February 2020, 107459|[3]Kojima S, et al. Clostridium botulinum type A progenitor toxin binds to Intestine-407 cells via N-acetyllactosamine moiety. Biochem Biophys Res Commun. 2005 Jun 3;331 (2) :571-6. |[4]Yoon KT, et al. Galectin-3 inhibits cardiac contractility via a tumor necrosis factor alpha-dependent mechanism in cirrhotic rats. Clin Mol Hepatol. 2022 Apr;28 (2) :232-241.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Galectin-3; Human Endogenous Metabolite

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