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Migrastatin

CAT: 0804-HY-121452Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-121452Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Migrastatin is a typical Fascin1 inhibitor. Migrastatin is isolated from a cultured broth of Streptomyces sp. MK929-43F1. Migrastatin inhibits tumor cell migration[1][2].
CAS Number
314245-65-3
UNSPSC
12352005
Target
Calcium Channel; nAChR
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/migrastatin.html
Solubility
10 mM in DMSO
Smiles
O=C(NC(C1)=O)CC1CCCC([C@H]([C@]2([H])/C(C)=C\[C@H]([C@@H]([C@H](/C=C/CC/C=C/C(O2)=O)OC)O)C)C)=O
Molecular Formula
C27H39NO7
Molecular Weight
489.60
References & Citations
[1]Montoro-García S, et al. Novel anti-invasive properties of a Fascin1 inhibitor on colorectal cancer cells. J Mol Med (Berl) . 2020;98 (3) :383-394.|[2]Nakae K, et al. Migrastatin, a new inhibitor of tumor cell migration from Streptomyces sp. MK929-43F1. Taxonomy, fermentation, isolation and biological activities. J Antibiot (Tokyo) . 2000;53 (10) :1130-1136.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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