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Casirivimab

CAT: 0804-HY-P99341-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P99341-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Casirivimab (REGN10933) is a human monoclonal antibody that targets the SARS-CoV-2 virus, which causes COVID-19. Casirivimab is ineffective against COVID-19 variants. Casirivimab can be used in combination with Imdevimab , which alters the lung response of K18-hACE2 mice to the SARS-CoV-2 δ variant, effectively reducing viral load and improving symptoms[1][2].
CAS Number
2415933-42-3
Product Name Alternative
REGN10933
UNSPSC
12352203
Target
SARS-CoV
Type
Inhibitory Antibodies
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/casirivimab.html
Purity
95.0
Solubility
10 mM in DMSO
Smiles
[Casirivimab]
Molecular Weight
(145.24 kDa)
References & Citations
[1]Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD) : National Institute of Child Health and Human Development; 2006–. Casirivimab. 2022 May 15. |[2]Lee Tatham, et al. Ronapreve (REGN-CoV; casirivimab and imdevimab) reduces the viral burden and alters the pulmonary response to the SARS-CoV-2 Delta variant (B.1.617.2) in K18-hACE2 mice using an experimental design reflective of a treatment use case. Microbiol Spectr. 2024 Aug 6;12 (8) :e0391623.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Launched

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