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S1647

CAT: 0804-HY-168523Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-168523Size:1 Each
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Description
S1647 is a ASBT and SOAT dual inhibitor. S1647 can be used in the study of intrahepatic cholestasis, cholestatic pruritus, and obstipation[1].
CAS Number
259528-99-9
UNSPSC
12352211
Target
Apical Sodium-Dependent Bile Acid Transporter
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/s1647.html
Smiles
O=C(NC1=CC=C(Cl)C(Cl)=C1)C2=CC=CC=C2NS(=O)(C3=CC=CC([N+]([O-])=O)=C3)=O
Molecular Formula
C19H13Cl2N3O5S
Molecular Weight
466.29
References & Citations
[1]Wannowius M, et al. Structure-Activity Relationships and Target Selectivity of Phenylsulfonylamino-Benzanilide Inhibitors Based on S1647 at the SLC10 Carriers ASBT, NTCP, and SOAT. J Med Chem. 2024 Oct 17.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
T200838-01S1647

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