Palmitoyl 3-carbacyclic phosphatidic acid

• UNSPSC Description:

  Palmitoyl 3-carbacyclic phosphatidic acid (HY-139061) is a palmitoylated Carba-like cyclophosphatidic acid and an analog of lysophosphatidic acid (LPA). Palmitoyl 3-carbacyclic phosphatidic acid has different functions from LPA and can inhibit the activation of RhoA and inhibit the migration of melanoma cells. Palmitoyl 3-carbacyclic phosphatidic acid effectively inhibited experimental lung metastasis and reduced the number of tumor nodules in a B16-F0 xenograft mouse model[1].

• Target Antigen:

  LPL Receptor; ROCK

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Cytoskeleton;GPCR/G Protein;Stem Cell/Wnt;TGF-beta/Smad

• Field of Research:

  cancer

• Assay Protocol:

  https://www.medchemexpress.com/palmitoyl-3-carbacyclic-phosphatidic-acid.html

• Smiles:

  CCCCCCCCCCCCCCCC(OCC1CCP(O1)(O)=O)=O

• Molecular Weight:

  390.49

• References & Citations:

  [1]Uchiyama A, et al. Inhibition of transcellular tumor cell migration and metastasis by novel carba-derivatives of cyclic phosphatidic acid. Biochim Biophys Acta. 2007 Jan;1771(1):103-12.

• Shipping Conditions:

  Room temperature

• CAS Number:

  476310-22-2