GSK-3β inhibitor 11

GSK-3β inhibitor 11

• CAS Number: 536731-65-4
• UNSPSC Description: GSK-3β inhibitor 11 (compound 21) is a glycogen synthase kinase-3β (GSK-3β) inhibitor (IC50=10.02 μM). GSK-3β inhibitor 11 can be used in neurodegenerative disease research[1].
• Target Antigen: GSK-3
• Type: Reference compound
• Related Pathways: PI3K/Akt/mTOR;Stem Cell/Wnt
• Applications: Neuroscience-Neurodegeneration
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/gsk-3β-inhibitor-11.html
• Solubility: DMSO : 20.83 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: O=C1C2=C(C(N1CC(NC3=NC(C4=CC(OC)=CC=C4)=CS3)=O)=O)C=CC=C2
• Molecular Weight: 393.42
• References & Citations: [1]Fu G, et al. Pharmacophore Modeling, Ensemble Docking, Virtual Screening, and Biological Evaluation on Glycogen Synthase Kinase-3β. Mol Inform. 2014 Sep;33(9):610-26.
• Shipping Conditions: Blue Ice
• Clinical Information: No Development Reported