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Silymarin

CAT: 0804-HY-N7073-01Size: 250 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N7073-01Size:250 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Silymarin is an extract of the milk thistle (Silybum marianum) . Silymarin is an effective SARS-CoV-2 main protease (Mpro) inhibitor. Silymarin can significantly reduce tumor cell proliferation, angiogenesis as well as insulin resistance. Silymarin has the chemopreventive effect on hepatocellular carcinoma (HCC) . Silymarin has the potential for COVID-19 research[1][2][4].
CAS Number
65666-07-1
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
SARS-CoV
Type
Natural Products
Related Pathways
Anti-infection
Applications
Cancer-programmed cell death
Field of Research
Cancer; Infection; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/silymarin.html
Purity
82.50
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
[Silymarin]
Precautions
H302, H315, H319, H335
References & Citations
[1]Féher J, et al. Silymarin in the prevention and treatment of liver diseases and primary liver cancer. Curr Pharm Biotechnol. 2012 Jan;13 (1) :210-7.|[2]Sung-Hyun Kim, et al.Silymarin induces inhibition of growth and apoptosis through modulation of the MAPK signaling pathway in AGS human gastric cancer cells. Oncol Rep. 2019 Nov;42 (5) :1904-1914.|[3]Mina Khoshnoodi, et al. Possible involvement of nitric oxide in antidepressant-like effect of silymarin in male mice. Pharm Biol. 2015 May;53 (5) :739-45.|[4]Anna Maria Sardanelli, et al. SARS-CoV-2 Main Protease Active Site Ligands in the Human Metabolome. Molecules 2021, 26 (5), 1409.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched

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