Products for Research Use Only

Interleukin Antibody

CAT: 0013-GTR18795289Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR18795289Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CAT-2200 is a human monoclonal antibody (IgG1/lambda) targeting Interleukin-17A (IL-17A/CTLA-8) . IL-17A is a critical pro-inflammatory cytokine produced by Th17 cells, playing a central role in the pathology of autoimmune diseases such as psoriasis, rheumatoid arthritis, and multiple sclerosis. CAT-2200 specifically binds to the IL-17A homodimer, blocking its interaction with cell surface receptors (IL-17RA/IL-17RC), thereby effectively neutralizing the biological activity of IL-17A. Studies demonstrate that CAT-2200 significantly inhibits the IL-17A-induced release of downstream inflammatory mediators (e.g., IL-6, IL-8, and GRO-alpha) . This antibody is frequently used as a tool antibody or positive control for researching the IL-17A signaling pathway and its role in inflammatory responses.
Target
Interleukin
Clonality
Monoclonal
Conjugation
Unconjugated
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.