Products for Research Use Only

GPCR Antibody

CAT: 0013-GTR18795236-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR18795236-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Anti-GPR44/PTGDR2/CD294 Antibody is a humanized monoclonal antibody expressed in CHO cells targeting the GPCR GPR44 (CRTH2/PTGDR2) . Featuring a huIgG1 heavy chain and a hukappa light chain, it binds specifically to the extracellular domain of GPR44, blocking the binding of its ligand PGD2. This antagonism inhibits PGD2-induced Gi protein-coupled signaling, restoring intracellular cAMP levels and reducing calcium mobilization, thereby inhibiting the chemotaxis and activation of Th2 cells, eosinophils, and basophils.
Target
GPCR
Clonality
Monoclonal
Conjugation
Unconjugated
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.