IL-1 beta, Pig

• UNSPSC Description:

  IL-1 beta is a potent proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. IL-1 beta plays a key role in inflammation and immunologic reactions[1][2].  IL-1 beta Protein,Pig consists of 153 amino acids (A115-P267) and is expressed in E. coli.

• Type:

  Recombinant Proteins

• Assay Protocol:

  https://www.medchemexpress.com/cytokines/il-1-beta-protein-porcine.html

• Purity:

  95.00

• Smiles:

  MANVQSMECK LQDKDHKSLV LAGPHMLKAL HLLTGDLKRE VVFCMSFVQG DDSNNKIPVT LGIKGKNLYL SCVMKDNTPT LQLEDIDPKR YPKRDMEKRF VFYKTEIKNR VEFESALYPN WYISTSQAEQ KPVFLGNSKG RQDITDFTME VLSP

• Molecular Weight:

  Approximately 17.88 kDa

• References & Citations:

  [1]Jan Petrasek, et al. IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice. J Clin Invest. 2012 Oct;122(10):3476-89.|[2]Karina Zitta, et al. Interleukin-1beta regulates cell proliferation and activity of extracellular matrix remodelling enzymes in cultured primary pig heart cells. Biochem Biophys Res Commun. 2010 Sep 3;399(4):542-7.|[3]Kenichi Shimada, et al. Caspase-1 dependent IL-1β secretion is critical for host defense in a mouse model of Chlamydia pneumoniae lung infection. PLoS One. 2011;6(6):e21477.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Stored at -20°C for 2 years