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Others Antibody

CAT: 0013-GTR18795239-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR18795239-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MEDI-570 is a humanized IgG1 monoclonal antibody produced in CHO cells, targeting the inducible T-cell costimulator (ICOS/CD278) . Functioning as a potent agonist, it binds with high affinity to the ICOS receptor, mimicking and amplifying the costimulatory signal of its natural ligand, ICOS-L. This agonistic activity promotes the activation, proliferation, survival, and cytokine production of T cells, including effector T cells and T follicular helper (Tfh) cells. It is developed as a cancer immunotherapeutic agent designed to combat tumors by enhancing T-cell function.
Target
Others
Clonality
Monoclonal
Conjugation
Unconjugated
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.

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