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(-) -Denudatin B

CAT: 0804-HY-N3729-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N3729-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(-) -Denudatin B is an antiplatelet agent. (-) -Denudatin B relaxed vascular smooth muscle by inhibiting the Ca2+ influx through voltage-gated and receptor-operated Ca2+ channels[1]. And (-) -Denudatin B has nonspecific antiplatelet action
CAS Number
87402-88-8
Product Name Alternative
Denudatin B
UNSPSC
12352005
Target
Calcium Channel
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/minus-denudatin-b.html
Purity
97.88
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
CO[C@@]12C(O[C@@](C3=CC(OC)=C(C=C3)OC)([H])[C@H]1C)=CC(C(CC=C)=C2)=O
Molecular Formula
C21H24O5
Molecular Weight
356.41
References & Citations
[1]Yu SM, et al. Vasorelaxing effect in rat thoracic aorta caused by denudatin B, isolated from the Chinese herb, magnolia fargesii. Eur J Pharmacol. 1990;187 (1) :39-47.|[2]Teng CM, et al. Inhibition of thrombin- and collagen-induced phosphoinositides breakdown in rabbit platelets by a PAF antagonist--denudatin B, an isomer of kadsurenone. Thromb Res. 1990;59 (1) :121-130.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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