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PINK1 Antibody

CAT: 0013-GTR18789053-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18789053-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mouse monoclonal antibody to PINK1.
Product Name Alternative
Anti PINK1 antibody, anti Serine/threonine-protein kinase PINK1, mitochondrial antibody, anti BRPK antibody, anti PTEN-induced putative kinase protein 1 antibody
UniProt
Q9BXM7
Reactivity
Human
Immunogen
Recombinant PINK1 protein was used to produced this monoclonal antibody. Antigen Region: Unknown.
Target
PINK1
Clonality
Monoclonal
Clone
B50EV42X0X7
Conjugation
Unconjugated
Field of Research
Cell Biology
Dilution
WB: 1:100-500, IHC-P: 1:50-100, IF/ICC: 1:25
Form
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Molecular Weight
62769
References & Citations
Ordureau, Alban et al. Dynamics of PARKIN-Dependent Mitochondrial Ubiquitylation in Induced Neurons and Model Systems Revealed by Digital Snapshot Proteomics Mol Cell, 70, 211-227.e8 (2018)
Pubmed id
29656925
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Notes
For research use only.
Tested Applications
IF, IHC-P, WB
NCBI Accession Number
NP_115785.1
Host or Source
Mouse
Isotype
IgG1

UniProtKB · Q9BXM7

Serine/threonine-protein kinase PINK1, mitochondrial

PINK1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9BXM7
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PINK1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.1
Processing
Precursor
Secondary accessions
Q8N6T9, Q8NBU3, Q96DE4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingMagnesiumMetal-bindingNucleotide-binding

Biological process

Autophagy

Cellular component

CytoplasmMembraneMitochondrionMitochondrion inner membraneMitochondrion outer membrane

Disease

Disease variantNeurodegenerationParkinson diseaseParkinsonismPrimary mitochondrial disease

Molecular function

KinaseSerine/threonine-protein kinaseTransferase

PTM

Phosphoprotein

Domain

Transit peptide

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