Products for Research Use Only

Beclin 1 Antibody

CAT: 0013-GTR18789009-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18789009-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal antibody to Beclin 1
Product Name Alternative
Anti-APG6 antibody, anti-ATG 6 antibody, anti-ATG6 antibody, anti-ATG6 autophagy related 6 homolog antibody, anti-Beclin 1 autophagy related antibody, anti-Beclin-1 antibody, anti-Beclin1 antibody, anti-BECN 1 antibody, anti-Becn1 antibody, anti-BECN1_HUMAN antibody, anti-GT197 antibody, anti-Protein GT197 antibody, anti-VPS 30 antibody, anti-VPS30 antibody
UniProt
Q14457
Reactivity
Human, Mouse
Immunogen
Synthetic Peptide
Target
BECN1
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cancer Biology, Cell Biology, Infectious Disease & Virology, Metabolism Research, Microbiology
Dilution
WB: 1:1000, IHC-P: 1:50-100
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Molecular Weight
51896
References & Citations
Gravina, Giovanni Luca et al. Dual PI3K/mTOR inhibitor, XL765 (SAR245409), shows superior effects to sole PI3K [XL147 (SAR245408) ] or mTOR [rapamycin] inhibition in prostate cancer cell models Tumour Biol, 37, 341-351 (2016)
Pubmed id
26219891
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Notes
For research use only.
Prediction Reactivity
Bovine, Gallus
Tested Applications
IHC-P, WB
NCBI Accession Number
NP_003757.1
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · Q14457

Beclin-1

BECN1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q14457
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
BECN1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B2R6N7, O75595, Q9UNA8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Biological process

Antiviral defenseApoptosisAutophagyCell cycleCell divisionEndocytosisHost-virus interaction

Domain

Coiled coil

Cellular component

CytoplasmCytoplasmic vesicleEndoplasmic reticulumEndosomeGolgi apparatusMembraneMitochondrionNucleus