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BACE1 Antibody (N-term)

CAT: 0013-GTR18788942-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18788942-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Purified rabbit polyclonal antibody.
Product Name Alternative
Anti-Beta-secretase 1 [Precursor] antibody, anti-Beta-site APP cleaving enzyme 1 antibody, anti-Beta-site amyloid precursor protein cleaving enzyme 1 antibody, anti-Aspartyl protease 2 antibody, anti-Asp 2 antibody, anti-ASP2 antibody, anti-Membrane-associated aspartic protease 2 antibody, anti-Memapsin-2 antibody, anti-BACE1 antibody, anti-BACE antibody
UniProt
P56817
Reactivity
Human, Mouse
Immunogen
Synthetic Peptide
Target
BACE1
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cell Biology
Dilution
WB: 1:1000, IHC-P: 1:10-50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Molecular Weight
55764
References & Citations
Lu, Jing et al. An Anti-Parkinson's Disease Drug via Targeting Adenosine A2A Receptor Enhances Amyloid-β Generation and γ-Secretase Activity PLoS One, 11, e0166415 (2016)
Pubmed id
27835671
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Notes
For research use only.
Prediction Reactivity
Rat
Tested Applications
IHC-P, WB
NCBI Accession Number
NP_620429.1, NP_620427.1, NP_036236.1, NP_001193978.1, NP_620428.1
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · P56817

Beta-secretase 1

BACE1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P56817
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
BACE1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.23.46
Processing
Precursor
Secondary accessions
A0M8W7, B0YIU9, E9PE65, H7BXJ9, Q9BYB9, Q9BYC0, Q9BYC1, Q9UJT5, Q9ULS1
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationDisulfide bondGlycoproteinIsopeptide bondLipoproteinPalmitatePhosphoproteinUbl conjugationZymogen

Coding sequence diversity

Alternative splicing

Molecular function

Aspartyl proteaseHydrolaseProtease

Cellular component

Cell membraneCell projectionCytoplasmic vesicleEndoplasmic reticulumEndosomeGolgi apparatusLysosomeMembrane

Domain

SignalTransmembraneTransmembrane helix

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