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PIM1 Antibody

CAT: 0013-GTR18788187-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18788187-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal antibody to PIM1 or pim-1 whose expression can be detected in the blood cells but it is majorly expressive in the erythrocytes. It is found in the nucleus. It can perform functions like apoptotic processes and shows oncogenic activity through: the regulation of cell cycle progression and by phosphorylation and inhibition of proapoptotic proteins (BAD, MAP3K5, FOXO3) . It also acts as a regulator of homing and migration of bone marrow cells involving functional interaction with the CXCL12-CXCR4 signaling axis.
Product Name Alternative
Anti-Oncogene PIM 1 antibody, anti-Oncogene PIM1 antibody, anti-PIM 1 antibody, anti-pim 1 kinase 44 kDa isoform antibody, anti-Pim 1 kinase antibody, anti-pim 1 oncogene (proviral integration site 1) antibody, anti-Pim 1 oncogene antibody, anti-PIM antibody, anti-PIM1 antibody, anti-pim1 kinase 44 kDa isoform antibody, anti-Proto oncogene serine/threonine protein kinase Pim 1 antibody, anti-Proto-oncogene serine/threonine-protein kinase Pim-1 antibody, anti-Proviral integration site 1 antibody
UniProt
P11309
Reactivity
Human
Immunogen
Recombinant Protein
Target
PIM1
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cancer Biology, Signal Transduction
Dilution
WB - 1:1000, IHC-P - 1:10-50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Molecular Weight
35686
References & Citations
Xu, Jianwei et al. PIM-1 contributes to the malignancy of pancreatic cancer and displays diagnostic and prognostic value J Exp Clin Cancer Res, 35, 133 (2016)
Pubmed id
27596051
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Notes
For research use only.
Tested Applications
IHC-P, WB
NCBI Accession Number
NP_002639.1, NP_001230115.1
Host or Source
Rabbit
Isotype
Rabbit IgG

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