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Isaxonine

CAT: 0804-HY-W129456-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W129456-01Size:5 mg
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Description
Isaxonine acts as a modifier of the surface pH of the bilayer[1]. Isaxonine accelerates the rate of peripheral nerve regeneration, stimulate axonal sprouting and promote motor and sensory function recovery[2]. Isaxonine is a neurotrophic agent[3].
CAS Number
4214-72-6
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/isaxonine.html
Purity
99.54
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C)NC1=NC=CC=N1
Molecular Formula
C7H11N3
Molecular Weight
137.18
Precautions
H302, H315, H319, H335
References & Citations
[1]De Bleecker J, et al. Influence of isaxonine on the target phenomenon, muscle fibre size and neuromuscular junction in the tenotomized and denervated gastrocnemius muscle of the rat. Acta Neuropathol. 1986;69 (3-4) :337-340. |[2]J De Bleecker, et al. Influence of Isaxonine on the target phenomenon, muscle fibre size and neuromuscular junction in the tenotomized and denervated gastrocnemius muscle of the rat. Acta Neuropathol. 1986;69 (3-4) :337-40.|[3]C M Becker, et al. Nerve and muscle regeneration after axonal division in rats treated with Isaxonine phosphate (isopropylamino-2-pyrimidine phosphate) . Eur Surg Res. 1986;18 (6) :383-9.|[4]J De Reuck, et al. Influence of Isaxonine on reinnervation of the rat gastrocnemius muscle. Acta Neuropathol. 1987;72 (4) :406-8.|[5]A Davy, et al. [Hepatotoxicity of Isaxonine phosphate: 4 cases of severe subacute hepatitis]. Gastroenterol Clin Biol. 1984 Oct;8 (10) :715-9.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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