Narciclasine (Standard)

• UNSPSC Description:

  Narciclasine (Standard) is the analytical standard of Narciclasine. This product is intended for research and analytical applications. Narciclasine is a plant growth modulator. Narciclasine modulates the Rho/Rho kinase/LIM kinase/cofilin signaling pathway, greatly increasing GTPase RhoA activity as well as inducing actin stress fiber formation in a RhoA-dependent manner.

• Target Antigen:

  ROCK

• Type:

  Reference Standards

• Related Pathways:

  Cell Cycle/DNA Damage;Cytoskeleton;Stem Cell/Wnt;TGF-beta/Smad

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/narciclasine-standard.html

• Smiles:

  O=C1N[C@@]2([H])[C@H](O)[C@H](O)[C@@H](O)C=C2C3=C1C(O)=C4C(OCO4)=C3

• Molecular Weight:

  307.26

• References & Citations:

  [1]Lefranc F, et al. Narciclasine, a plant growth modulator, activates Rho and stress fibers in glioblastoma cells. Mol Cancer Ther. 2009 Jul;8(7):1739-50.|[2]Wahyuni DS, et al. The use of bio-guided fractionation to explore the use of leftover biomass in Dutch flower bulb production as allelochemicals against weeds. Molecules. 2013 Apr 17;18(4):4510-25.

• Shipping Conditions:

  Room temperature

• CAS Number:

  29477-83-6