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CAT: 0013-GTR18775336-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR18775336-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AO-176 is a humanized anti-CD47 IgG2 monoclonal antibody. It induces tumor phagocytosis by blocking the interaction between CD47 and SIRPα. AO-176 preferentially binds to tumor cells over normal cells and directly kills tumor cells through a cell-autonomous mechanism, rather than via antibody-dependent cellular cytotoxicity (ADCC) . In tumor xenograft models, AO-176 demonstrates dose-dependent antitumor activity. This compound is applicable in cancer research, such as studies involving lymphoma.
Target
Others
Clonality
Monoclonal
Conjugation
Unconjugated
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.

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