NF-κB Antibody

CAT: 0013-GTR18775192-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR18775192-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

PE0116 is a fully humanized CD137 agonistic monoclonal antibody, generated from immunized Harbor H2L2 transgenic mice. Acting as a ligand blocker, PE0116 activates NF-κB signaling, which significantly enhances T cell proliferation and increases cytokine secretion in vitro. In the MC38 tumor model, PE0116 demonstrates strong antitumor activity.

Target

NF-κB

Clonality

Monoclonal

Conjugation

Unconjugated

Field of Research

Signal Transduction

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

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