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Evacetrapib

CAT: 0804-HY-13327-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-13327-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Evacetrapib is a potent and selective of CETP inhibitor, which inhibits human recombinant CETP protein (IC50 5.5 nM) and CETP activity in human plasma (IC50 36 nM) in vitro.
CAS Number
1186486-62-3
Product Name Alternative
LY2484595
UNSPSC
12352005
Hazard Statement
H361, H400, H410
Target
CETP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Evacetrapib.html
Concentration
10mM
Purity
98.89
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C([C@H]1CC[C@H](CN2CCC[C@H](N(CC3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)C4=NN(C)N=N4)C5=CC(C)=CC(C)=C52)CC1)O
Molecular Formula
C31H36F6N6O2
Molecular Weight
638.65
Precautions
H361, H400, H410
References & Citations
[1]Cao G, et al. Evacetrapib is a novel, potent, and selective inhibitor of cholesteryl ester transfer protein that elevates HDL cholesterol without inducing aldosterone or increasing blood pressure. J Lipid Res. 2011 Dec;52 (12) :2169-76.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3

Alternative Products

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2558-5Evacetrapib
A4377-200Evacetrapib (LY2484595)
FE65020-01Evacetrapib monohydrate

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