JAK-IN-26
CAT:
804-HY-153701-01
Size:
100 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
JAK-IN-26
- CAS Number: 2417134-93-9
- UNSPSC Description: JAK-IN-26 (Compound 2) is a JAK inhibitor. JAK-IN-26 inhibits IFN-α2b induced p-STAT3 in Jurkat cells (IC50: 17.2 nM). JAK-IN-26 has superior pharmacokinetic properties[1].
- Target Antigen: JAK
- Type: Reference compound
- Related Pathways: Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/jak-in-26.html
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C(C1CC1)NC2=NC=C(C(NC3=CC=CC(C4=NN(C)C=N4)=C3OC)=C2)C(CC)=O
- Molecular Weight: 420.46
- References & Citations: [1]Zhou M, et al. Pyridine derivatives as TYK2 kinase inhibitors and preparation thereof. China, CN113563309 A 2021-10-29.|[2]Zhou Mengguang. Pyridine derivative and preparation method and application thereof. Patent. CN113563309.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported