Recombinant Human Membrane cofactor protein (CD46), partial

Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Dry Ice Shipment: No

Alternative Products

Cat	Name
MBS147120-01	Recombinant Human Membrane Metalloendopeptidase
MBS147120-02	Recombinant Human Membrane Metalloendopeptidase
MBS147120-03	Recombinant Human Membrane Metalloendopeptidase
MBS141437-02	Recombinant Human Membrane Metalloendopeptidase
MBS141437-04	Recombinant Human Membrane Metalloendopeptidase
MBS147120-04	Recombinant Human Membrane Metalloendopeptidase
rAP-1458	Membrane Metalloendopeptidase Human Recombinant
MBS141437-01	Recombinant Human Membrane Metalloendopeptidase
MBS141437-03	Recombinant Human Membrane Metalloendopeptidase
22060333-1	Human Glomerular Basement Membrane (Recombinant)

CAT:

399-CSB-MP004939HUc7-03

Size:

20 µg

Price:

Ask

For price, please contact [email protected].

Recombinant Human Membrane cofactor protein (CD46), partial

Gene Name: CD46
UniProt: P15529
Expression Region: 35-328aa
Organism: Homo sapiens
Target Sequence: CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVLPPSSTKPPALSHSVSTSSTTKSPASSASGPRPTYKPPVSNY
Tag: C-terminal 6xHis-tagged
Source: Mammalian cell
Field of Research: Immunology
Assay Type: Developed Protein
Relevance: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. ; (Microbial infection) A number of viral and bacterial pathogens seem to bind MCP in order to exploit its immune regulation property and directly induce an immunosuppressive phenotype in T-cells.; (Microbial infection) Acts as a receptor for Adenovirus subgroup B2 and Ad3. ; (Microbial infection) Acts as a receptor for cultured Measles virus. ; (Microbial infection) Acts as a receptor for Herpesvirus 6/HHV-6. ; (Microbial infection) May act as a receptor for pathogenic bacteria Neisseria and Streptococcus pyogenes.
Purity: Greater than 90% as determined by SDS-PAGE.
Activity: Not Test
Length: Partial
Form: Liquid or Lyophilized powder
Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Molecular Weight: 34.9 kDa
References & Citations: "Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype." Kemper C., Chan A.C., Green J.M., Brett K.A., Murphy K.M., Atkinson J.P. Nature 421:388-392 (2003)
Storage Conditions: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
Protein Length: Partial

Complementary Product Range

Our range of products, including Recombinant Human Membrane cofactor protein (CD46), partial, falls within the same field of application and can be used across various research projects. These products are carefully selected for their high performance and reliability, supporting the diverse needs of modern laboratories. Whether for ongoing studies or future experiments, they are designed to help researchers achieve their scientific goals. Here are some related products that may be of interest for similar or future applications:

Each item in our collection, is tested for precision and quality, ensuring dependable solutions for your research. As we continue to incorporate the latest advancements, Gentaur ensures that our product range remains relevant and versatile, providing you with the tools needed for both current and future projects.

Find us on

Cat	Name
CSB-EP004939HU1-01	Recombinant Human Membrane cofactor protein (CD46), partial
CSB-MP004939HU-B-01	Recombinant Human Membrane cofactor protein (CD46), partial
CSB-MP004939HU-B-02	Recombinant Human Membrane cofactor protein (CD46), partial
CSB-MP004939HUc7-03	Recombinant Human Membrane cofactor protein (CD46), partial
CSB-CF768224HU-02	Recombinant Human Membrane progestin receptor alpha (PAQR7)
CSB-MP613581HU(A5)-03	Recombinant Human Membrane protein MLC1 (MLC1)-VLPs
CSB-CF757672HIX-02	Recombinant Human coronavirus NL63 Membrane protein (M)
CSB-EP018091HU-01	Recombinant Human Phospholipase A2, membrane associated (PLA2G2A)
CSB-EP018091HU-02	Recombinant Human Phospholipase A2, membrane associated (PLA2G2A)
CSB-MP004939HUc7-02	Recombinant Human Membrane cofactor protein (CD46), partial